个人简介:
高岩,男,汉族,1992年11月生,山西运城人,校聘副教授,硕士生研究生导师。2022年1月参加工作,华中农业大学水产动物医学专业毕业,研究生学历,博士学位。现任必威BETWAY官网水产科学系专业教师。以第一作者发表SCI期刊论文3篇,主持或参与科研课题4项。
研究方向:
鱼类天然免疫调控、水产病毒致病机制、抗病毒药物筛选
主讲课程:
本科:水产药物学,细胞生物学
研究生:水产动物疾病研究方法与实验技术、水生动植物疾病诊治及防控
教科研项目:
1.2024-2026,河北省自然科学基金青年科学基金项目(C2024204011):IFIT家族蛋白在SVCV感染并诱导斑马鱼脑部炎症中的作用及调控机制研究,主持,在研;
2.2022-2024,河北省省属高等学校基本科研项目(KY2022071):不同温度下SVCV感染鱼类细胞的转录组学研究,主持,在研;
3.2022-2025,betway必威人才引进科研基金(YJ2022002):SVCV入侵斑马脑组织诱导炎症的机制研究,主持,在研;
4.2020-2023,国家自然科学基金面上项目(31972834), SVCV通过泛素化降解Viperin_sv1实现免疫逃逸的分子机制, 参与, 结题。
论文论著:
Gao Y, Xiang YH, Li C, et al. TRIM33 promotes spring viremia of carp virus replication by degrading the antiviral protein viperin_sv1[J]. Aquaculture, 2021, 542:736837.
Gao Y, Xiang YH, Wang F, et al. The N protein of spring viremia of carp virus promotes the ubiquitination and degradation of viperin_sv1 to escape from the fish innate immunity[J]. Aquaculture, 2021, 538.
Gao Y, Li C, Shi L, et al. Viperin_sv1 promotes RIG-I expression and suppresses SVCV replication through its radical SAM domain[J]. Developmental and Comparative Immunology, 2021:104166.
Zhang Y,Gao Y, Li C, et al.Parabacteroides distasonisregulates the infectivity and pathogenicity of SVCV at different water temperatures[J]. Microbiome, 2024, 12(1):1-19.
Song YF,GaoY, Christer H, et al. Upstream regulators of apoptosis mediates methionine-induced changes of lipid metabolism[J]. Cellular Signalling, 2018, 51:176-190.
Li C, Shi L,Gao Y,et al. HSC70 Inhibits Spring Viremia of Carp Virus Replication by Inducing MARCH8-Mediated Lysosomal Degradation of G Protein[J]. Frontiers in immunology, 2021, 12:724403.
Shi L, Li C,Gao Y, et al. STUB1 activates antiviral response in zebrafish by promoting the expression of RIG-I[J]. Fish & Shellfish Immunology, 2022(123).
Wei CC, Wu K,Gao Y, et al. Magnesium Reduces Hepatic Lipid Accumulation in Yellow Catfish (Pelteobagrus fulvidraco) and Modulates Lipogenesis and Lipolysis via PPARA, JAK-STAT, and AMPK Pathways in Hepatocytes[J]. Journal of Nutrition, 2017:1070.
Luo Z, Ye HM,Gao Y, et al. Chlorella additive increased growth performance, improved appetite and immune response of juvenile crucian carp Carassius auratus[J]. Aquaculture Research, 2018, 49(10).
联系方式:
办公电话:0335-3150025
办公邮箱:hyxygyan@hebau.edu.cn
通讯地址:河北省秦皇岛市海港区河北大街东段52号